1. A baccalaureate or associate degree in one of the physical or biological sciences

2. A baccalaureate or associate degree in other disciplines with successful completion of courses in the following areas: college algebra, physics, chemistry, human anatomy, and physiology

3. National certification as a registered medical technologist (MT)

4. National certification as a registered radiographer (RT)

5. Licensed as a registered nurse (RN)

6. National certification as a registered diagnostic medical sonographer (RDMS)

7. National certification as a radiation therapist (RTT)

Four years full-time (or 8000 hours) of clinical experience in nuclear medicine technology under the supervision of a physician (MD/DO) board certified in nuclear radiology (ABR) or nuclear medicine (ABNM) or isotopic pathology (ABP) or an authorized physician user of radioactive materials with special competency in nuclear medicine.

The NMTCB defines full-time clinical experience as 40 hours per week (2,000 hours per year). Overtime and call time are excluded. Technologists who work part-time may apply for the examination if their total experience is equivalent to the full-time requirements as stated previously. Employment in temporary positions may not be included. Clinical experience obtained outside the United States will be evaluated on a case-by-case basis to determine equivalency to U.S. standards. The candidate must also provide documentation of US equivalency regarding the credentials of the supervising physician.

Satisfactory completion of a minimum of fifteen (15) contact hours of coursework in each of the following areas: radiopharmacy, nuclear medicine instrumentation and radiation safety. Only coursework from an accredited college or university, accredited nuclear medicine program or approved continuing education credits recognized by NMTCB, such as VOICE/ECE, will be accepted.